<div>Background: Mouse mammary tumor is a common neoplasm of the species. Mice is an established model for human breast cancer studies and in recent times for transgenic studies. Hemangiomas are tumors of blood vascular system. Hemangioma with breast cancer is reported in human beings. Presented study describes an unusual case of concurrent mouse mammary tumor and cavernous hemangioma from Mizoram, India. 
 
Methods: A mortality of 8 out of a colony of 25 female albino mice was observed due to mammary tumors. Dead mice were thoroughly necropsied and tissue samples were collected from different parts of each tumor mass and fixed in neutral buffered formalin. The fixed tissues were processed for hematoxylin and eosin staining by routine paraffin embedding, microtomy and staining protocol.&nbsp; 
 
Result: Gross examination revealed variable sized tumors on abdomen of affected mice. Histopathology revealed two different forms of mammary tumor viz, acinar and solid mammary carcinoma. Most peculiar finding was remarkable presence of large, endothelial lined cavernous spaces with presence of stagnant blood. These were diagnosed as cavernous hemangioma. Perusal of available literature did not reveal any report of cavernous hemangioma occurring with mouse mammary tumor, while it is found in other species including human beings.</div>

<div>Spontaneous Mammary Tumor with Concurrent Cavernous Hemangioma in Albino Mice- A Rare Case Report from Mizoram, India</div>

Background: Splenic tumors are among the most common intra-abdominal neoplasms in dogs and often present with nonspecific clinical signs, making early diagnosis challenging.&nbsp; 
 
Methods: The study was conducted on 82 dogs presented with suspected splenic disorders at Madras Veterinary College Teaching Hospital, Chennai, for a period of two years between January 2024 and January 2026. All cases underwent detailed clinical examination, hematological and biochemical analyses, radiographic evaluation and ultrasonographic assessment. Ultrasonography was used to evaluate splenic size, echotexture, margins and metastatic involvement. Fine-needle aspiration cytology was performed under ultrasound guidance and histopathological examination was carried out in selected cases for definitive diagnosis.&nbsp; 
 
Result: Common clinical signs included anorexia, abdominal distension and abdominal pain. Hematological findings revealed anemia, leukocytosis and thrombocytopenia, while biochemical alterations included hypoproteinemia. Radiography showed splenomegaly, intestinal displacement and abdominal masses, whereas ultrasonography consistently detected splenomegaly, heterogeneous masses, irregular margins and metastasis. Cytological and histopathological examination identified various lesions, including hemangiosarcoma, lymphoma, hemangioma and hematoma. Ultrasonography proved to be a sensitive tool for detection and preliminary characterization, though definitive diagnosis required confirmatory techniques. Although hemangiosarcoma was frequently suspected based on ultrasonographic features and clinical presentation, histopathological confirmation was obtained in fewer cases due to limited access to biopsy samples. The study emphasizes the importance of integrating clinical examination with diagnostic imaging, cytology and histopathology for the evaluation of splenic tumors in dogs.

Spontaneous Mammary Tumor with Concurrent Cavernous Hemangioma in Albino Mice- A Rare Case Report from Mizoram, India

Radiographic and Ultrasonographic Features of Splenic Tumors in Dogs: A Clinicopathological Study